What we do
Today, in the mere amount of novel approaches and medical devices and biomaterials on the market, one of the major problems is to identify the ones which have the potential to be truly transforming for human health. Consequently, at no other time has the need for a robust, bidirectional information flow between basic and clinical scientists been so necessary in order to close the gap that has opened up between biomedical researchers and the patients in need of their discoveries.
There is an urgent need to refocus on patient-oriented research, conducted by capable and motivated scientists with dedicated time away from the escalating pressure of clinical service demands.
Second, it refers to a more and more complex environment, growing costs and increasing regulatory burden with academic institutions, often showing artificial barriers that inevitably lead to a dilution of research time and a reduced attention devoted to the given research mission. As a consequence, they encounter more and more difficulties in recruitment and retention of human subjects in clinical trials – a fact which results in a considerable delay in the completion of important clinical studies.
Last but not least, third, there are cultural and administrative barriers between different specialties that often impede scientific progress. Based on the fact that new discoveries are often made at the interface of pre-existing disciplines, it would be of utmost importance to take the opportunities for enriching partnerships with other institutions, industry companies and qualified experts.
Our scientific approach is based on three key elements:
Focused on patient-centered research
All scientific efforts and clincial attempts should be based on a mindset that considers external evidence (available scientific data), internal evidence (clincial expertise of surgeons / relevance of data) and patient-centered variables as equal parameters when designing a scientific study. The benefit for the patient must be the main objective of each effort and not personal or financial interests of the involved persons, companies or institutions. It is the aim of the group to close the gap between basic and clinical research and to translate the results into the language of the clinician and general practitioner.
Based on a concept for a new approach to tackling complexity (interconnected thinking)
Undoubtlessly, we are faced with an increasingly complex situation and the inadequacy of conventional ways of thinking is becoming progressively more evident. Although perfectly planned in itself, the outcomes of studies and consequences of clinical interventions to the intricate fabric can have fatal repercussions like delayed after-effects due to the technical sensitivity of the surgical intervention or questionable indication and benefits for the patients. Based on the Malik Sensitivity Model®, each relevant question will be evaluated regarding the influencing factors and, before finalizing the study protocol, the data set will be reduced to a few system relevant key dynamics in a feedback diagram of the whole system (significance of feedback cycles).
Benefit from an interdisciplinary cooperation
The Research Group aims for networking and bunching competence within the different fields of periodontology and oral implantology as well as in other areas like medical basic research, industrial engineering, media and behaviour research. To comply with this condition, each project will be led by members of the Clinical Research Foundation, supported and complemented by qualified persons and elected experts. For this, the already existing and broad network of the CRF with academic institutions worldwide, microbiological laboratories, animal research and other competence centers will be helpful and extensively used.